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Merck
모든 사진(1)

주요 문서

PHL89824

Withaferin A

phyproof® Reference Substance

동의어(들):

4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid δ-lactone, Withaferine

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About This Item

실험식(Hill 표기법):
C28H38O6
CAS Number:
Molecular Weight:
470.60
MDL number:
UNSPSC 코드:
41116107
NACRES:
NA.24

Grade

primary reference standard

제품 라인

phyproof® Reference Substance

분석

≥95.0% (HPLC)

제조업체/상표

PhytoLab

응용 분야

food and beverages

형식

neat

저장 온도

2-8°C

SMILES string

C[C@H]([C@H]1CC(C)=C(CO)C(=O)O1)[C@H]2CC[C@H]3[C@@H]4C[C@H]5O[C@]56[C@@H](O)C=CC(=O)[C@]6(C)[C@H]4CC[C@]23C

InChI

1S/C28H38O6/c1-14-11-21(33-25(32)17(14)13-29)15(2)18-5-6-19-16-12-24-28(34-24)23(31)8-7-22(30)27(28,4)20(16)9-10-26(18,19)3/h7-8,15-16,18-21,23-24,29,31H,5-6,9-13H2,1-4H3/t15-,16-,18+,19-,20-,21+,23-,24+,26+,27-,28+/m0/s1

InChI key

DBRXOUCRJQVYJQ-CKNDUULBSA-N

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일반 설명

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

애플리케이션


  • Catalysis driven by an amyloid-substrate complex: Research demonstrates the role of buffer concentrates in maintaining optimal pH and stability conditions during biochemical reactions involving amyloid substrates, critical for developing new therapeutic agents (Sawazaki et al., 2024).

  • High throughput microfluidics-based synthesis of PEGylated liposomes for precise size control and efficient drug encapsulation: This research utilizes buffer concentrates to manage the pH and ionic strength during the microfluidic synthesis of PEGylated liposomes, critical for achieving size precision and high encapsulation efficiency in drug delivery systems (Akar et al., 2024).

  • Development of Analytical Quality by Design RP-HPLC Method and Its Validation for Estimation of Gefitinib from Bulk, Tablet Dosage Form and Complex Nanoformulation: Buffer concentrates play a vital role in this study, optimizing the RP-HPLC method for precise quantification of gefitinib, a critical aspect in ensuring the quality and efficacy of pharmaceutical products (More et al., 2024).



기타 정보

This compound is commonly found in plants of the genus: withania

법적 정보

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

438.8 °F

Flash Point (°C)

226 °C


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