53571-U

Ascentis^® Express 90 Å F5 (2.7 μm) HPLC Columns

L × I.D. 15 cm × 2.1 mm, HPLC Column

• 동의어(들): Core-shell (SPP) Fused Core PFP HPLC column
• UNSPSC 코드: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

속성

• product name: Ascentis^® Express F5, 2.7 μm HPLC Column, 2.7 μm particle size, L × I.D. 15 cm × 2.1 mm
• material: stainless steel column
• Agency: suitable for USP L43
• 제품 라인: Ascentis^®
• 특징: endcapped
• 제조업체/상표: Ascentis^®
• 포장: 1 ea of
• 파라미터: 60 °C temp. range; 600 bar max. pressure (9000 psi)
• 기술: HPLC: suitable; LC/MS: suitable; UHPLC-MS: suitable; UHPLC: suitable
• 길이 × I.D.: 15 cm × 2.1 mm
• 표면적: 135 m²/g
• 불순물: <5 ppm metals
• 기질: Fused-Core particle platform; superficially porous particle
• 기질 활성군: PFP (pentafluorophenyl) phase
• 입자 크기: 2.7 μm
• 공극 크기: 90 Å pore size
• 작동 pH: 2-8
• 응용 분야: food and beverages
• 분리 기술: reversed phase

설명

일반 설명

The pentafluorophenylpropyl stationary phase of Ascentis Express F5 provides a stable reversed phase packing with electron-deficient phenyl rings due to the presence of electronegative fluorines.In addition to forming pi-pi and mildly steric interactions, F5 phases also retain compounds by polar interactions. Ascentis Express F5 can be used for basic, acidic, or neutral compounds with alternate selectivity from C18.

애플리케이션

• Liquid chromatographic determination of lumacaftor in the presence of ivacaftor and identification of five novel degradation products using high-performance liquid chromatography ion trap time-of-flight mass spectrometry.: This study employs the Ascentis^® Express F5, 2.7 μm HPLC Column to enhance the resolution and sensitivity in the analysis of lumacaftor and ivacaftor, critical medications for treating cystic fibrosis. The method provides significant insights into the stability and degradation pathways of these drugs, facilitating improved drug formulation and storage conditions (Ozcan et al., 2023).
• Stability-indicating LC-MS/MS and LC-DAD methods for robust determination of tasimelteon and high resolution mass spectrometric identification of a novel degradation product.: Utilizing the Ascentis^® Express F5, 2.7 μm HPLC Column, this research develops advanced analytical techniques for tasimelteon, a treatment for non-24-hour sleep-wake disorder. The methods ensure accurate quantification and stability assessment, crucial for clinical efficacy and patient safety (Ozcan et al., 2020).

법적 정보

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany