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Merck
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Key Documents

50137-U

Supelco

LiChrospher® RP-18 (5 µm) HPLC Columns

L × I.D. 25 cm × 4 mm, HPLC Column

동의어(들):

TM=["LiChrospher"] C18 HPLC column

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About This Item

UNSPSC 코드:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

LiChrospher® RP-18 HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4 mm

material

stainless steel column

Quality Level

Agency

suitable for USP L1

제품 라인

LiChrospher®

특징

endcapped: no

제조업체/상표

LiChrospher®

포장

1 ea of

라벨링 범위

21% Carbon loading

파라미터

≤70 °C temp. range
400 bar pressure (5801 psi)

기술

HPLC: suitable

길이 × I.D.

25 cm × 4 mm

표면적

350 m2/g

기질

octadecyl
silica particle platform
fully porous particle

기질 활성군

C18 (octadecyl) phase

입자 크기

5 μm

공극 크기

100 Å

작동 pH

2-7.5

응용 분야

food and beverages

분리 기술

reversed phase

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일반 설명

LiChrospher® RP-18 HPLC column (L × I.D. 25 cm × 4 mm) is found to be reliable and high versatile. Suitable for reversed-phase high performance liquid chromatography (RP-HPLC) of acidic, neutral and weakly basic compounds, according to L1 USP specifications.

애플리케이션


  • HPLC-UV and GC-MS Methods for Determination of Chlorambucil and Valproic Acid in Plasma for Further Exploring a New Combined Therapy of Chronic Lymphocytic Leukemia.: This study developed and validated HPLC-UV and GC-MS methods for determining chlorambucil and valproic acid in plasma, aiming to explore their combined therapy for chronic lymphocytic leukemia. The LiChrospher® RP-18 HPLC Column was instrumental in achieving the separation and quantification (Lipska et al., 2021).

  • Rapid Determination of Metronidazole and 2-Hydroxymetronidazole in Murine Blood Plasma.: This research utilized the LiChrospher® RP-18 HPLC Column for the rapid determination of metronidazole and its metabolite in murine blood plasma, highlighting its effectiveness in pharmacokinetic studies (Zemanová et al., 2022).

  • Application of chemometric approach for development and validation of high performance liquid chromatography method for estimation of ropinirole hydrochloride.: This paper presents a chemometric approach to developing and validating an HPLC method for estimating ropinirole hydrochloride, utilizing the LiChrospher® RP-18 column for precise and accurate results (Fatima et al., 2019).

  • A New Solid-Phase Extraction Method for Determination of Pantoprazole in Human Plasma Using High-Performance Liquid Chromatography.: The study developed a novel solid-phase extraction method for determining pantoprazole in human plasma using HPLC with the LiChrospher® RP-18 column, achieving high sensitivity and specificity (Zendelovska et al., 2019).

  • Application of an HPLC-MS/MS method for Teicoplanin drug substance and related impurities, part 2: Identity assignment of related impurities.: This research employed the LiChrospher® RP-18 column in an HPLC-MS/MS method to identify and assign related impurities in teicoplanin drug substances, demonstrating the column′s capability in impurity profiling (Tengattini et al., 2019).

추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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