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Merck
모든 사진(1)

Key Documents

47782

Supelco

D-α-Tocopherol succinate

analytical standard

동의어(들):

Vitamin E succinate

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C33H54O5
CAS Number:
Molecular Weight:
530.78
Beilstein:
4038233
EC Number:
MDL number:
UNSPSC 코드:
12164500
PubChem Substance ID:

Grade

analytical standard

CofA

current certificate can be downloaded

특징

standard type fat soluble vitamin

포장

ampule of 100 mg

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

형식

neat

저장 온도

2-8°C

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1

InChI

1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1

InChI key

IELOKBJPULMYRW-NJQVLOCASA-N

일반 설명

D-α-Tocopherol succinate is a potent antioxidant tocopherol with antitumor activity and inhibits colon cancer liver metastases.

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Vitamin E succinate inhibits colon cancer liver metastases
Barnett TK, et al.
The Journal of Surgical Research, 106(2), 292-298 (2002)
Vitamin E succinate promotes breast cancer tumor dormancy
Malafa PM, et al.
The Journal of Surgical Research, 93(1), 163-170 (2000)
Dasheng Wang et al.
Journal of medicinal chemistry, 52(18), 5642-5648 (2009-08-28)
This study is aimed at the pharmacological exploitation of alpha-tocopheryl succinate (1) to develop potent antiadhesion agents. Considering the structural cooperativity between the phytyl chain and the carboxylic terminus in determining the antiadhesion activity, our structural optimization led to compound
Pengfei Xu et al.
Biomaterials, 35(26), 7574-7587 (2014-06-06)
Metastasis is one of the major obstacles for the successful therapy of breast cancer. Although increased candidate drugs targeting cancer metastasis are tested, their clinical translation is limited by either serve toxicity or low efficacy. In present work, a nano-drug
Yanyun Xu et al.
International journal of pharmaceutics, 495(2), 792-797 (2015-09-28)
Our recent publication showed that VES-dFdC nanocapsules in pure water could be obtained via the self-assembling of VES-dFdC prodrug synthesized by coupling gemcitabine (dFdC) with vitamin E succinate (VES). To prepare the intravenous injection nanoformulation, we present here a novel

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