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11023AST

Supelco

Astec® CHIROBIOTIC® V Chiral (5 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

동의어(들):

Vancomycin Chiral Column

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About This Item

UNSPSC 코드:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Astec® CHIROBIOTIC® V Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

material

stainless steel column

Quality Level

Agency

suitable for USP L88

설명

HPLC Column

제품 라인

Astec®

포장

pkg of 1 ea

제조업체/상표

Astec®

파라미터

0-45 °C temperature
80-110 bar pressure (1200-1500 psi)

기술

HPLC: suitable
LC/MS: suitable

길이 × I.D.

15 cm × 4.6 mm

기질

High-purity silica gel particle platform
fully porous particle

기질 활성군

vancomycin phase

입자 크기

5 μm

공극 크기

100 Å

pH 범위

3.5-7.0

분리 기술

chiral

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Neutral molecules, amides, acids, esters and amines show considerable enantioselectivity on these vancomycin-based CSPs. A wide variety of secondary and tertiary amines have been separated on the CHIROBIOTIC® V in the polar ionic mode. The CHIROBIOTIC® V has demonstrated many of the separation characteristics of protein-based stationary phases, but with exceptional stability and much higher sample capacity. Some chiral analytes have been resolved that have not been reported separated on any other chiral stationary phase. CHIROBIOTIC® V and V2 differ in their bonding chemistry the pore size of the support particle, giving them different selectivity and preparative capacity.

  • Bonded phase: Vancomycin
  • Operating pH range: 3.5 - 7.0
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å (CHIROBIOTIC® V) or 200 Å (CHIROBIOTIC® V2)

애플리케이션



  • Development and validation of an UFLC-MS/MS method for enantioselectivity determination of d,l-thero-methylphenidate, d,l-thero-ethylphenidate and d,l-thero-ritalinic acid in rat plasma and its application to pharmacokinetic study.: This study highlights the application of UFLC-MS/MS combined with Astec® CHIROBIOTIC® V Chiral HPLC Column for the enantioselective analysis of various therapeutic agents in rat plasma, providing a crucial methodological advancement for pharmacokinetic research ( Zhang et al., 2016).


추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

J P Bagnall et al.
Journal of chromatography. A, 1249, 115-129 (2012-07-04)
This paper presents and compares for the first time two chiral LC-QTOF-MS methodologies (utilising CBH and Chirobiotic V columns with cellobiohydrolase and vancomycin as chiral selectors) for the quantification of amphetamine, methamphetamine, MDA (methylenedioxyamphetamine), MDMA (methylenedioxymethamphetamine), propranolol, atenolol, metoprolol, fluoxetine
Analysis of the enantiomers of citalopram and its demethylated metabolites using chiral liquid chromatography
Kosel, M., et al.
Journal of Chromatography. B, Biomedical Applications, 719 (1-2), 234-238 (1998)
HPLC separation technique for analysis of bufuralol enantiomers in plasma and pharmaceutical formulations using a vancomycin chiral stationary phase and UV detection
Hefnawy, Mohamed M., et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 856 (1-2), 328-336 (2007)
Ana R Ribeiro et al.
Chemosphere, 95, 589-596 (2013-11-05)
Microbial degradation is the most important process to remove organic pollutants in Waste Water Treatment Plants. Regarding chiral compounds this process is normally enantioselective and needs the suitable analytical methodology to follow the removal of both enantiomers in an accurate
Hisham Hashem et al.
Journal of chromatography. A, 1218(38), 6727-6731 (2011-08-23)
In this study, a method for enantioseparation of terbutaline and salbutamol was established using Chirobiotic V column as a stationary phase. Polar ionic mode applying mobile phase containing ammonium nitrate in 100% ethanol, pH 5.1 was found to give the

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