WH0004790M1
Monoclonal Anti-NFKB1 antibody produced in mouse
clone 2E6, purified immunoglobulin, buffered aqueous solution
동의어(들):
Anti-DKFZp686C01211, Anti-EBP1, Anti-KBF1, Anti-MGC54151, Anti-NFKBp105, Anti-NFKBp50, Anti-NFkappaB, Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
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모든 사진(5)
About This Item
결합:
unconjugated
application:
ELISA (i)
IF
PLA
WB
IF
PLA
WB
클론:
2E6, monoclonal
종 반응성:
human
citations:
4
기술:
indirect ELISA: suitable
indirect immunofluorescence: suitable
proximity ligation assay: suitable
western blot: 1-5 μg/mL
indirect immunofluorescence: suitable
proximity ligation assay: suitable
western blot: 1-5 μg/mL
추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
2E6, monoclonal
양식
buffered aqueous solution
종 반응성
human
기술
indirect ELISA: suitable
indirect immunofluorescence: suitable
proximity ligation assay: suitable
western blot: 1-5 μg/mL
동형
IgG1κ
GenBank 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... NFKB1(4790)
관련 카테고리
일반 설명
NFKB1 (nuclear factor κB subunit 1) is a dimeric transcription factor. It belongs to the REL family. This gene is located on human chromosome 4q24.
면역원
NFKB1 (AAH51765, 860 a.a. ~ 969 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI
Sequence
MDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI
생화학적/생리학적 작용
NFKB1 (nuclear factor κB subunit 1) controls the maturation of NK (natural killer) cells and effector functions. This gene helps in the upregulation of intrauterine adhesion inflammatory factors, hence NFKB1 plays a major role in inflammatory diseases.
물리적 형태
Solution in phosphate buffered saline, pH 7.4
법적 정보
GenBank is a registered trademark of United States Department of Health and Human Services
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
가장 최신 버전 중 하나를 선택하세요:
EBV induces persistent NF-?B activation and contributes to survival of EBV-positive neoplastic T- or NK-cells
Takada H, et al.
PLoS ONE, 12(3) (2017)
NFKB1 regulates human NK cell maturation and effector functions
Lougaris V, et al.
Clinical Immunology (Orlando, Fla.) (2017)
Elevated NF-?B signaling in Asherman syndrome patients and animal models
Wang X, et al.
Oncotarget, 8(9), 15399-15406 (2017)
J Spring
FEBS letters, 400(1), 2-8 (1997-01-02)
For the growing fraction of human genes with identified functions there are often homologues known from invertebrates such as Drosophila. A survey of well established gene families from aldolases to zinc finger transcription factors reveals that usually a single invertebrate
Y Yu et al.
British journal of cancer, 111(3), 515-524 (2014-06-13)
Ovarian cancer has the highest mortality rate of the gynaecological cancers. Although cisplatin (CDDP) is an effective treatment for ovarian cancer, recurrence is frequent and leads to death. The objective was to explore the role and possible mechanisms of platelet-activating
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