UC126

4-Hydroxymephenytoin

• 동의어(들): (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylhydantoin, (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimididazolidine-2,4-dione
• 실험식(Hill 표기법): C₁₂H₁₄N₂O₃
• CAS Number: 61837-65-8
• Molecular Weight: 234.25
• MDL number: MFCD00142316
• UNSPSC 코드: 12161501
• PubChem Substance ID: 24724640
• NACRES: NA.77

속성

• 양식: solid
• Quality Level: 200
• 색상: white
• mp: 153-154 °C
• 저장 온도: 2-8°C
• SMILES string: CCC1(NC(=O)N(C)C1=O)c2ccc(O)cc2
• InChI: 1S/C12H14N2O3/c1-3-12(8-4-6-9(15)7-5-8)10(16)14(2)11(17)13-12/h4-7,15H,3H2,1-2H3,(H,13,17)
• InChI key: OQPLORUDZLXXPD-UHFFFAOYSA-N

설명

일반 설명

CYP2C19 metabolite of mephenytoin.

애플리케이션

4-Hydroxymephenytoin has been used for developing ultra performance LC (UPLC)- tandem mass spectrometry (MS/MS) assays for evaluating cytochrome P450 (CYP) probe drugs and their relevant metabolites in human urine or plasma samples. 4-hydroxymephenytoin has also been used for developing sub-2-micron particle LC/MS/MS-based methods for analyzing CYP450 probe substrate metabolites.

생화학적/생리학적 작용

4-Hydroxymephenytoin catabolism displays genetic polymorphism and is a direct indicator of Cytochrome P450 2C19 (CYP2C19) activity. Detection and quantification of 4-hydroxymephenytoin in biological samples by HPLC method is well optimized.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)