추천 제품
분석
≥98% (HPLC)
형태
solid
광학 활성
[α]22/D -39.0 to -32.0°, c = 0.5 in methanol(lit.)
저장 조건
desiccated
색상
white
solubility
H2O: 13 mg/mL
저장 온도
2-8°C
SMILES string
O.Cl.CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3
InChI
1S/C19H26Cl2N2O.ClH.H2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23;;/h8-9,12,17-18H,2-7,10-11,13H2,1H3;1H;1H2/t17-,18-;;/m0../s1
InChI key
UWPRPWMHQDPOFR-MPGISEFESA-N
유전자 정보
human ... OPRK1(4986)
애플리케이션
(−)-trans-(1S,2S)-U-50488 hydrochloride hydrate (U-50488) has been used as a κ-opioid receptor (KOR) agonist has been used to study its effect on the increase of tidal volumes in adult red-eared slider turtles (Trachemys scripta).
생화학적/생리학적 작용
Potent κ opioid receptor agonist; more potent enantiomer of (±)-trans-U-50488.
제조 메모
(−)-trans-(1S,2S)-U-50488 hydrochloride hydrate is soluble in water at 13 mg/ml.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Proceedings of the National Academy of Sciences of the United States of America, 88(2), 360-364 (1991-01-15)
Opioids and opioid peptides have been shown by numerous laboratories to modulate various parameters of the immune response, but little attention has been given to the type of opioid receptor that might be involved. This study focuses on the in
Stereospecific inhibition of gastro-intestinal transit by κ-opioid agonists in mice.
European Journal of Pharmacology, 155, 329-329 (1991)
American journal of physiology. Regulatory, integrative and comparative physiology, 295(5), R1599-R1612 (2008-09-12)
For ectothermic vertebrates, such as reptiles, the effects of opioid receptor subtype activation on breathing are poorly understood. On the basis of previous studies on mammals and lampreys, we hypothesized that mu- and delta-opioid receptor (MOR and DOR, respectively) activation
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