U1006

Uridine 5′-triphosphate trisodium salt solution

HPLC purified, aqueous solution for RNA polymerase transcription

• 동의어(들): UTP
• MDL number: MFCD00044310
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24900622
• NACRES: NA.52

속성

• 생물학적 소스: yeast (Candida Utilis)
• 분석: ≥95 (HPLC)
• 형태: liquid
• 농도: 100 mM in H₂O (adjusted to pH 7 with Trizma^®; base)
• 색상: colorless
• 외래 활성: DNase and RNase, none detected
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
• InChI key: MMJGIWFJVDOPJF-LLWADOMFSA-K
• 유전자 정보: human ... P2RY2(5029) ; rat ... P2ry2(29597)

설명

애플리케이션

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca²⁺ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).

생화학적/생리학적 작용

UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.

Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

법적 정보

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable