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Merck
모든 사진(1)

Key Documents

T9145

Sigma-Aldrich

Thyroglobulin from bovine thyroid

(For Gel Filtration Chromatography)

동의어(들):

Tg

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.56

생물학적 소스

bovine thyroid

Quality Level

형태

powder

분자량

~670 kDa

기술

bioconjugation: suitable

UniProt 수납 번호

저장 온도

−20°C

유전자 정보

cow ... TG(280706)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Thyroglobulin is used for antibody purification and characterization. Thyroglobulin has been used in studies assessing the monitoring of differentiated thyroid cancer as well as to develop an accurate diagnostic tool for patients with autoimmune thyroid diseases.
Often used as a carrier protein for the production of antibodies. Its advantage is the large number of tyrosine residues that can be used for conjugation using the diazo reaction.

생화학적/생리학적 작용

Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by thyroid-stimulating hormone (TSH) from the pituitary. Because its expression is unique to the thyroid, it is a sensitive indicator of recurrence or metastasis of thyroid cancer that has been treated by thyroid ablation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Andrew N Hoofnagle et al.
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HIV-1 vaccine design aims to develop an immunogen that elicits broadly neutralizing antibodies against a desired epitope, while eliminating responses to off-target regions of HIV-1 Env. We report characterization of Ab1245, an off-target antibody against the Env gp120-gp41 interface, from
Perrine Munier et al.
Annales de biologie clinique, 69(6), 721-725 (2011-11-30)
Thyroglobuline (Tg) is a large molecule of high molecular weight mainly indicated in monitoring differentiated thyroid cancer (DTC), its measurement remains difficult. We report the case of a patient who underwent total thyroidectomy for a poorly differentiated thyroid insular carcinoma.
Akio Yoshida et al.
The Journal of clinical endocrinology and metabolism, 94(2), 442-448 (2008-12-04)
Pendrin is an apical protein of thyroid follicular cells, responsible for the efflux of iodide into the follicular lumen via an iodide-chloride transport mechanism. It is unknown whether pendrin is recognized by autoantibodies. Our objective was to examine the prevalence
Kouame Adou et al.
Analytical chemistry, 81(24), 10186-10192 (2009-11-21)
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문서

With the emergence of mass spectrometry for the clinical measurement of proteins in biological matrices, the development of biological reference materials will continue to grow in importance.

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