추천 제품
일반 설명
Apo-transferrin human is a glycoprotein, possessing homologous carboxyl and amino domain. Both the domain binds to one molecule of iron. Only 30% of transferrin is saturated with iron in the amino domain. Apo-transferrin in human is encoded by the gene TF which is localized on human chromosome 3q22.1.
애플리케이션
Apo-Transferrin human has been used:
- to determine the competitive binding of bismuth to albumin and transferrin by fast performance liquid chromatography (FPLC)
- to study titanium-transferrin complex by electrochemical method
- in the preparation of transferrin solution and in the formation of conjugates with ruthenium-complexes for cellular viability studies
생화학적/생리학적 작용
Apo-transferrin is an iron transport protein. The concentration of transferrin in blood plasma is about 35 μM. Transferrin also functions in the transport of therapeutic, diagnostic and toxic ions like Ga3+, Ru3+ and Al3+. Polymorphism in TF gene has pathological implications in Parkinson′s disease.
Apo-transferrin is required for the survival and differentiation of oligodendroglial cells.
기타 정보
Non-heme iron-transport protein.
결합
Similar to T 2252
면책조항
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
이미 열람한 고객
Binding of bismuth to serum proteins: implication for targets of Bi (III) in blood plasma
Sun H and Szeto KY
Journal of Inorganic Biochemistry, 94(1-2), 114-120 (2003)
New polydentate Ru (III)-Salan complexes: Synthesis, characterization, anti-tumour activity and interaction with human serum proteins
Matos CP, et al.
Inorgorganica Chimica Acta, 394, 616-626 (2013)
Pooled analysis of iron-related genes in Parkinson's disease: association with transferrin
Rhodes SL, et al.
Neurobiology of Disease, 62, 172-178 (2014)
Direct electrochemistry of the Ti (IV)-transferrin complex: Probing into the transport of Ti (IV) by human serum transferrin
Shen M, et al.
Electrochemical Communications, 13(2), 114-116 (2011)
Junko Iijima et al.
Fukushima journal of medical science, 67(2), 64-70 (2021-08-11)
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문서
How transferrin and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of transferrin.
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