T1450

Anti-γ-Tubulin (LL-17) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-γ-Tubulin (LL-17)
• MDL number: MFCD06411816
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 48 kDa
• 종 반응성: Caenorhabditis elegans
• 기술: western blot: 0.75-1.5 μg/mL using whole extract of C. elegans.
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: Caenorhabditis elegans ... Tbg-1(176361)

설명

일반 설명

γ-Tubulin is a widely expressed and highly conserved protein within the microtubule organizing centers (MTOCs) or centrosome in eukaryotic cells. It is a member of the tubulin superfamily of proteins, which includes α and β tubulin and the newly discovered centrosomal-associated proteins, δ and ε tubulin. γ-Tubulin abundance is less than 1% of the level of either α or β tubulin.

면역원

synthetic peptide corresponding to the C-terminus of C. elegans γ-tubulin (amino acids 428-444) with N-terminal added cysteine, conjugated to KLH. This sequence is highly specific for C. elegans γ-tubulin, and not found in γ-tubulin sequences of other species or other members of the tubulin family such as α-, β-, δ-, and ε-tubulins.

애플리케이션

Anti-γ-Tubulin (LL-17) antibody produced in rabbit has been used in immunoblotting.

생화학적/생리학적 작용

γ-Tubulin has an essential role in microtubule nucleation by the centrosomes. γ-Tubulin does not polymerize with α-tubulin/β-tubulin, but instead it is localized to the centrosome and to the cytoplasm. γ-Tubulin is found as part of a large protein complex containing at least five other proteins and has a shape of a ring (γ-tubulin ring complex, γ-TuRC) that is roughly the same diameter as a microtubule. γ-Tubulin binds the microtubule minus ends and is responsible for mediating the link between microtubules and the centrosome.

표적 설명

γTubulin (LL-17) is a widely expressed and highly conservedprotein within the microtubule organizing centers (MTOCs) or centrosome in eukaryotic cells.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable