모든 사진(1)
About This Item
Linear Formula:
Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Thr-Asn-Val-Phe-Asn-Ala-Thr-Phe-Glu-Ile-Trp-His-Asp-Gly-Glu-Phe-Gly-Thr
CAS Number:
Molecular Weight:
3741.10
UNSPSC 코드:
12352200
NACRES:
NA.32
추천 제품
일반 설명
The TAT-BECLIN-1 (autophagy activator) peptide is derived from a region of the autophagy protein, beclin 1, attached to the HIV-1 Tat protein transduction domain. The peptide includes 11 amino acids at the N terminus derived from the Tat protein transduction domain, 18 amino acids (267–284 aa) from beclin 1 at the C terminus and a GG linker.
생화학적/생리학적 작용
The TAT-BECLIN-1 (autophagy activator) peptide reduces the accumulation of polyglutamine aggregates and pathogen replication in vitro. This peptide is also found to reduce the mortality of mice infected by different viruses. The TAT-BECLIN-1 peptide is predicted to stimulate cell death via autophagy.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Identification of a candidate therapeutic autophagy-inducing peptide.
Shoji-Kawata S, et al.
Nature, 494(7436), 201-201 (2013)
Autosis is a Na+, K+-ATPase?regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia?ischemia.
Liu Y, et al.
Proceedings of the National Academy of Sciences of the USA, 110(51), 20364-20371 (2013)
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