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Merck
모든 사진(1)

주요 문서

T0688

Sigma-Aldrich

Anti-Transforming Growth Factor-β1 antibody produced in chicken

affinity isolated antibody, lyophilized powder

동의어(들):

Anti-TGF-β1

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About This Item

MDL number:
UNSPSC 코드:
51111800
NACRES:
NA.41

생물학적 소스

chicken

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

lyophilized powder

종 반응성

human

기술

neutralization: suitable
western blot: suitable

UniProt 수납 번호

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... TGFB1(7040)

관련 카테고리

일반 설명

Transforming Growth Factor-β1 (TGF β1) is a multifunctional protein that can stimulate or inhibit cellular proliferation. Mesenchymal origin cells are stimulated by TGF β1 while T and B lymphocytes, keratinocytes, hepatocytes and epithelial cells are inhibited by TGF β1. It facilitates in tissue growth and differentiation by participating in myogenesis, osteogenesis, adipogenesis, chondrogenesis, epithelial cell differentiation and immune cell function. Anti-Transforming Growth Factor-β1 antibody can be used in neutralization assay. Chicken anti-TGF β1 reacts specifically with recombinant human TGF-β1 or TGF-β1.2.

특이성

The antibody will neutralize the biological activity of recombinant human TGF-β1 and porcine TGF-β1.2.

면역원

Recombinant human TGF-β1 expressed in CHO cells.

애플리케이션

Anti-Transforming Growth Factor-β1 antibody can be used in western blotting.

물리적 형태

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

J H Kehrl et al.
The Journal of experimental medicine, 163(5), 1037-1050 (1986-05-01)
This study examines the potential role of transforming growth factor beta (TGF-beta) in the regulation of human T lymphocyte proliferation, and proposes that TGF-beta is an important autoregulatory lymphokine that limits T lymphocyte clonal expansion, and that TGF-beta production by
G D Shipley et al.
Cancer research, 46(4 Pt 2), 2068-2071 (1986-04-01)
Type beta transforming growth factor-growth inhibitor (TGF beta/GI) causes normal human prokeratinocytes to arrest growth predominantly in the G1 phase of the cell cycle within 48 h after log phase cultures are exposed to the factor in serum-free medium. The
S Cheifetz et al.
Cell, 48(3), 409-415 (1987-02-13)
A new homodimer form of transforming growth factor-beta (TGF-beta), TGF-beta 2, has been identified in porcine blood platelets. TGF-beta 2 is homologous to ordinary TGF-beta (TGF-beta 1), which is also present in platelets. TGF-beta 1.2, a heterodimer containing one TGF-beta
C B Childs et al.
Proceedings of the National Academy of Sciences of the United States of America, 79(17), 5312-5316 (1982-09-01)
High concentrations of fetal bovine serum induced colony formation in soft agar by anchorage-dependent, nontransformed mouse AKR-2B and rat NRK cells. The colony-stimulating activity in fetal bovine serum was precipitated by 45% saturated ammonium sulfate and migrated in molecular sieve
I Hayashi et al.
Journal of cellular physiology, 125(1), 82-90 (1985-10-01)
Primary monolayer cultures of adult rat hepatocytes can be induced to undergo DNA synthesis in serum-free medium in the presence of insulin, glucagon, and epidermal growth factor (three factors). We have found that hepatocyte DNA synthesis is affected not only

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