SRP8059

Jagged-2 (human): FC (human)

recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)

• 동의어(들): Alpha-ketoglutarate-dependent dioxygenase FTO, Protein jagged-2, hJ2
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 재조합: expressed in HEK 293 cells
• 분석: ≥90% (SDS-PAGE)
• 양식: lyophilized
• 분자량: ~150 kDa by SDS-PAGE
• 불순물: <0.1 EU/μgtested
• UniProt 수납 번호: Q9Y219
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... JAG2(3714)

설명

일반 설명

Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.

서열

Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.

물리적 형태

Lyophilized. Contains PBS + 0.02 % CHAPS.

재구성

Reconstitute with 100μl sterile water.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable