SRP8037

IL-36γ mouse

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized

• 동의어(들): Interleukin-1 family member 9, Interleukin-36γ, SSI-3
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 제품명: IL-36γ mouse, recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)
• 생물학적 소스: mouse
• 재조합: expressed in E. coli
• 결합: untagged
• 분석: >95% (SDS-PAGE)
• 양식: lyophilized
• 분자량: ~17 kDa
• 포장: pkg of 10 μg
• 불순물: <0.01 EU/μg endotoxin, tested
• 색상: white
• UniProt 수납 번호: Q8R460
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: mouse ... Il36g(215257)

설명

일반 설명

IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

물리적 형태

Lyophilized from PBS and 0.5% trehalose.

재구성

Reconstitute with 100 μL deionized water.

기타 정보

IL-36gamma (mouse) (aa 13-164) is untagged.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable