SRP6522

Ubiquitin-TAMRA-labeled (TMR-Ub)

≥95% (SDS-PAGE)

• 동의어(들): CEP80, HUBCEP80, RPS27A, Ribosomal Protein S27a, UBA80, UBB, UBCEP1, UBCEP80
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 분석: ≥95% (SDS-PAGE)
• 양식: liquid
• 분자량: 9.133 kDa
• 포장: pkg of 50 μg
• 농도: 8 mg/mL
• 배송 상태: dry ice
• 저장 온도: −70°C

설명

일반 설명

Post-translational modification of proteins by ubiquitin (Ub) is a key regulatory process that impacts almost all cellular functions. Ubiquitylation occurs through isopeptide linkage between the C-terminus of Ub and the e-amino group of a lysine (Lys) residue on the target substrate [1]. Ub itself has seven Lys residues (6, 11, 27, 29, 33, 48, and 63), any of which can participate in further ubiquitylation, generating polyUb chains [2, 3]. Monitoring the ubiquitylation of target proteins or the growth of polyubiquitin chains has traditionally been carried out with either radiolabeled or epitope-tagged ubiquitin requiring long and laborious detection methods. Fluorescently labeled ubiquitin provides a rapid, facile technique for studying ubiquitin conjugation in vitro. Unlike others, TheTAMRA-labeled ubiquitin carries a single TAMRA molecule attached at a defined location and avoids modification of either the N-terminus or Lys side chains.

물리적 형태

≥ 8 mg/mL in PBS.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable