SRP6340

IL18BP human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 동의어(들): IL18BPa, Interleukin-18-binding protein
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥90% (SDS-PAGE)
• 양식: liquid
• 분자량: 20 kDa (187 aa, 31-194 aa + His Tag)
• 포장: pkg of 100 μg
• 농도: 1 mg/mL
• UniProt 수납 번호: O95998
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... IL18BP(10068)

설명

일반 설명

IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn′s disease. Recombinant human IL18BP protein, fused to His-tag at N-terminus, was expressed in E.coli.

물리적 형태

1 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable