SRP5268

HDAC9, active, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 동의어(들): DKFZp779K1053, HD7, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, KIAA0744, MITR
• CAS Number: 1428902-50-4
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in baculovirus infected Sf9 cells
• 분석: ≥70% (SDS-PAGE)
• 형태: buffered aqueous glycerol solution
• 특이 활성도: 199-299 RLU/min·ng
• 분자량: ~77 kDa
• NCBI 수납 번호: NM_058176
• 응용 분야: cell analysis
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... HDAC9(9734)

설명

일반 설명

HDAC9 or MIRT belongs to the histone deacetylase /acuc/apha family and is a component of the histone deacetylase complex. HDAC9 gene is orthologous to the Xenopus and mouse MITR genes (MEF2-interacting transcription repressor). HDAC9 represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 is a calcium-sensitive transcriptional repressor of MEF2. Binding of calmodulin to HDAC9 leads to its dissociation from MEF2, relieving MEF2 from the transcriptional repression. HDAC9 is a signal-responsive transcriptional repressor in mouse skeletal muscle that is downregulated upon denervation.

물리적 형태

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

제조 메모

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable