추천 제품
생물학적 소스
Xenopus sp.
재조합
expressed in baculovirus infected Sf9 cells
제품 라인
PRECISIO®
분석
≥70% (SDS-PAGE)
양식
buffered aqueous glycerol solution
특이 활성도
186-290 nmol/min·mg
분자량
~103 kDa
NCBI 수납 번호
응용 분야
cell analysis
배송 상태
dry ice
저장 온도
−70°C
유전자 정보
Xenopus laevis ... prkca(447031)
일반 설명
Protein kinase C-α (PKC-α) is a member of the PKC family of serine- and threonine-specific protein kinases that can be activated by calcium and the secondary messenger diacylglycerol. The protein is expressed in the dorsal ectoderm of Xenopus.
생화학적/생리학적 작용
Protein kinase C-α (PKC-α) has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint and cell volume control. It has been identified as a fundamental regulator of cardiac contractility and Ca2+ handling in myocytes.
물리적 형태
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
제조 메모
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
법적 정보
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Protein kinase C isozymes have distinct roles in neural induction and competence in Xenopus.
Cell, 68(6), 1021-1029 (1992)
PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Nature Medicine, 10(3), 248-254 (2004)
aPKC phosphorylates p27Xic1, providing a mechanistic link between apicobasal polarity and cell-cycle control.
Developmental Cell, 31(5), 559-571 (2014)
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