콘텐츠로 건너뛰기
Merck
모든 사진(2)

주요 문서

모든 문서 보기

SRP5087

Sigma-Aldrich

SOK1, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

동의어(들):

DKFZp686J1430, STK25, YSK1

로그인조직 및 계약 가격 보기
모든 사진(2)

About This Item

UNSPSC 코드:
12352204
NACRES:
NA.32

재조합

expressed in baculovirus infected Sf9 cells

제품 라인

PRECISIO® Kinase

분석

≥70% (SDS-PAGE)

양식

buffered aqueous glycerol solution

특이 활성도

9.4-12.6 nmol/min·mg

분자량

~76 kDa

NCBI 수납 번호

NM_006374

배송 상태

dry ice

저장 온도

−70°C

유전자 정보

human ... STK25(10494)

일반 설명

SOK1 or oxidant stress-response kinase-1 is a serine/threonine kinase that is activated by autophosphorylation and by reactive oxygen intermediates, but is not activated by growth factors, alkylating agents, cytokines, or environmental stresses. SOK1 is expressed ubiquitously with highest expression in brain and testis. SOK1 regulates cell death after chemical anoxia, as its down-regulation by RNA interference enhances cell survival. SOK1 entry into the nucleus is important for the cell death response since SOK1 mutants unable to enter the nucleus do not induce cell death.

물리적 형태

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

제조 메모

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

법적 정보

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
M143-1

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Carole L C Poon et al.
Developmental cell, 47(5), 564-575 (2018-11-22)
Hippo-like pathways are ancient signaling modules first identified in yeasts. The best-defined metazoan module forms the core of the Hippo pathway, which regulates organ size and cell fate. Hippo-like kinase modules consist of a Sterile 20-like kinase, an NDR kinase
C M Pombo et al.
The EMBO journal, 15(17), 4537-4546 (1996-09-02)
Mammalian homologs of the yeast protein kinase, Sterile 20 (Ste20), can be divided into two groups based on their regulation and structure. The first group, which includes PAK1, is regulated by Rac and Cdc42Hs, and activators have been identified. In
Emilio Nogueira et al.
The Journal of biological chemistry, 283(23), 16248-16258 (2008-03-28)
SOK1 is a Ste20 protein kinase of the germinal center kinase (GCK) family that has been shown to be activated by oxidant stress and chemical anoxia, a cell culture model of ischemia. More recently, it has been shown to be

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.