SRP4634

VEGF-C from mouse

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 동의어(들): VEGFC, Vascular Endothelial Growth Factor-C
• MDL number: MFCD03458368
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: mouse
• 재조합: expressed in E. coli
• 분석: ≥90% (SDS-PAGE)
• 양식: lyophilized
• 효능: >200 ng/mL ED₅₀
• 분자량: ~18.0 kDa
• 포장: pkg of 10 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 불순물: endotoxin, tested
• NCBI 수납 번호: P97953
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: mouse ... Vegfc(22341)

설명

일반 설명

VEGF-C (vascular endothelial growth factor-C) is a member of the VEGF family of structurally related proteins. The gene encoding this protein is localized on mouse chromosome 8. The product here (VEGF-C from mouse) is a 129 amino acid recombinant protein that lacks the N-terminal and C-terminal extensions and contains only the middle third VEGF homology domain. Mouse VEGF-C exhibits about 85% homology with human and 97% homology with rat VEGF-C.

생화학적/생리학적 작용

VEGF-C (vascular endothelial growth factor-C) has a role in lymphangiogenesis. It functions via the VEGF receptor-3 (VEGFR-3). Studies have shown that lymphatic endothelial cells do not form sprouting capillaries without VEGF-C. It has also been observed that this protein stimulates tumor lymphangiogenesis in xenotransplanted and transgenic mouse models of cancer.

물리적 형태

Lyophilized from acetic solution with 50 μg BSA per 1 μg VEGF-C.

재구성

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in 0.1% acetic acid to a concentration of 0.1-1.0 mg/mL.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable