SRP4561

Resistin from rat

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• 동의어(들): ADSF, Adipose tissue-specific secretory factor, C/EBP-ε-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-α-like 2, Cysteine-rich secreted protein FIZZ3, RSTN
• MDL number: MFCD03792461
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: rat
• 재조합: expressed in E. coli
• 분석: ≥95% (SDS-PAGE)
• 형태: lyophilized
• 분자량: ~11.9 kDa
• 포장: pkg of 25 μg
• 불순물: endotoxin, tested
• NCBI 수납 번호: NP_653342
• UniProt 수납 번호: Q8CJE0
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: rat ... Retn(246250)

설명

일반 설명

Resistin is a new member to of the family of adipocyte-secreted proteins. The biological functions of resistin, as well as its molecular target, are largely unknown. Whether it promotes or antagonizes insulin action is still unclear. Recombinant rat Resistin is an 11.9 kDa protein consisting of 94 amino acid residues and 16 additional amino acids residues-His Tag.
Resistin is an adipocytokine secreted by fat tissues and is localized to pancreatic α-cells in rat.

애플리케이션

Resistin from rat has been used to study the effect of resistin on gonadotropins and local ovarian hormone-induced steroidogenesis.

생화학적/생리학적 작용

Resistin mediates energy homeostasis and inflammation process. Upregulation of resistin is observed in obesity. It is also known to increase blood glucose level and might promote insulin resistance. Thus, it might influence type 2 diabetes. Resistin might be linked to insulin resistance mediated myocardial infarction (MI). In rats, overexpression of resistin is observed in myocardial infarction and cardiac dysfunction.

물리적 형태

Lyophilized from 20 mM Tris, pH 8.0.

재구성

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable