SRP3325

Uterglobin Peptide

≥98% (HPLC), human recombinant, expressed in E. coli

• 동의어(들): Clara cell phospholipid-binding protein, Secretoglobin family 1A member 1, Urinary protein 1
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• product name: UTERGLOBULIN human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥98% (HPLC); ≥98% (SDS-PAGE)
• 형태: lyophilized
• 분자량: 8.0 kDa
• 포장: pkg of 50 μg
• 불순물: endotoxin, tested
• UniProt 수납 번호: P11684
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... SCGB1A1(7356)

설명

일반 설명

Uteroglobin, also known as clara cell phospholipid-binding protein or CC10, is a member of the secretoglobin superfamily. It is secreted from nonciliated cells in the epithelial lining of bronchioles, also referred as Clara cells. Uteroglobin is encoded by the gene mapped to human chromosome 11q12.2 – 13.1. Recombinant Human Uteroglobin is an 8.0kDa homodimeric protein consisting of 142 amino acid residues.

생화학적/생리학적 작용

Uteroglobin functions as an immunomodulatory and anti-inflammatory protein. Uteroglobin might play a vital role in regulation of airway inflammation. Elevated level of uteroglobin has been observed in fallopian tubes of tubal ectopic pregnant women and in female patients with pelvic inflammatory disease. Uteroglobin level is reduced in serum of asthmatic patients with a long duration of the disease. Uteroglobin stimulates the growth of preimplantation blastocysts and it functions as a carrier and/or scavenger of progesterone, decreasing its toxicity to the early developing embryo. Uteroglobin has the capacity to prevent both chemotaxis and phagocytosis of monocytes and neutrophils.

물리적 형태

Lyophilized from 1 x PBS

재구성

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable