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Merck
모든 사진(1)

Key Documents

SRP3233

Sigma-Aldrich

RELM-gamma from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

동의어(들):

Resistin-like gamma

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About This Item

UNSPSC 코드:
12352202
NACRES:
NA.32

생물학적 소스

mouse

재조합

expressed in E. coli

분석

≥98% (HPLC)
≥98% (SDS-PAGE)

형태

lyophilized

분자량

9.2 kDa

포장

pkg of 25 μg

기술

cell culture | mammalian: suitable

불순물

<0.1 EU/μg endotoxin, tested

색상

white

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

mouse ... RETNIG(245195)

일반 설명

RELMγ belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The other three known members of this family; Resistin, RELMα, and RELMβ, are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMγ is most closely related to RELMα, but is distinctly secreted to bone marrow, spleen, lung, and in peripheral blood granulocytes. The physiological role of RELMγ may include the promotion or regulation of promyelocytic differentiation, although the specific molecular targets of RELMγ have not been identified. Recombinant murine RELMγ is a 9.2 kDa monomeric protein containing 88 amino acid residues.

생화학적/생리학적 작용

RELMγ belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. Recombinant murine RELMg is a 9.2 kDa monomeric protein containing 88 amino acid residues.

서열

EGTLESIVEK KVKELLANRD DCPSTVTKTF SCTSITASGR LASCPSGMTV TGCACGYGCG SWDIRDGNTC HCQCSTMDWA TARCCQLA

물리적 형태

Lyophilized with no additives.

재구성

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

B Gerstmayer et al.
Genomics, 81(6), 588-595 (2003-06-05)
We have identified RELMgamma, a novel member of the resistin-like molecule/found in inflammatory zone (RELM/FIZZ) family in mice and rats. Microarray and real-time RT-PCR experiments revealed a repression of RELMgamma mRNA in nasal respiratory epithelium of cigarette smoke-exposed versus untreated

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