SRP2122

CTF1, GST tagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE)

• 동의어(들): CTF, CTF/NFI, NF-1, NF-I
• UNSPSC 코드: 12352202
• NACRES: NA.26

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: ≥70% (SDS-PAGE)
• 형태: frozen liquid
• 분자량: ~36.8 kDa
• 포장: pkg of 10 μg
• 농도: 650 μg/mL
• 색상: colorless to clear
• NCBI 수납 번호: X12492
• UniProt 수납 번호: Q16619
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human herpesvirus 2 ... CTF-1(1489)

설명

생화학적/생리학적 작용

The CCAAT-box binding protein 1 (CTF1, also called NF-I or NF-1) is a proline-rich transcription activator. It selectively activates transcription of genes that contain GCCAAT consensus sequence in the promoter region, including human Ha-Ras, alpha-globin, hsp70 and many other cellular and viral genes. Cloning and functional characterization of the protein revealed that CTF1 contains a N-terminal DNA binding domain and a C-terminal proline-rich activation domain. CTF1 was shown to interact with the general transcription factor IIB (TFIIB) and facilitate the recruitment of TFIIB to TBP-DNA complexes, with the forkhead thyroid transcription factor TTF2 to regulate hormone-dependent transcription of thyroperoxidase gene, as well as other receptor proteins to synergize hormone receptor-responsive activation.

물리적 형태

Clear and colorless frozen liquid solution

제조 메모

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable