SRP0327

PADI-2 human

recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)

• 동의어(들): Peptidyl arginine deiminase, type II
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 생물학적 소스: human
• 재조합: expressed in baculovirus infected Sf9 cells
• 분석: ≥60% (SDS-PAGE)
• 형태: aqueous solution
• 분자량: 77 kDa
• 포장: pkg of 10 μg
• NCBI 수납 번호: NM_007365
• UniProt 수납 번호: Q9Y2J8
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... PADI2(11240)

설명

일반 설명

Human PADI2, also known as Peptidyl arginine deiminase, type II, (GenBank Accession No. NM_007365), amino acids 1-665 (end) with C-terminal FLAG-tag, MW= 77kDa, expressed in a Baculovirus infected Sf9 cell expression system. Peptidyl arginine deiminase, protein-2 (PADI2) is mapped to human chromosome 1p36. It is expressed in Sertoli cells at the time of testicular development.

애플리케이션

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. PADI-2 human has been used in in vitro binding assays.

생화학적/생리학적 작용

Peptidyl arginine deiminase, protein-2 (PADI2) promotes protein citrullination and represses the multiplication of cells. It helps to transform the amino acid arginine in a protein into amino acid citrulline. PADI2 participates in epigenetic mechanisms. It is linked with rheumatoid arthritis.

물리적 형태

Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/uL Flag peptide, 3 mMDTT, and 20% Glycerol.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable