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Merck
모든 사진(2)

주요 문서

SRP0245

Sigma-Aldrich

DYRK2 Active human

recombinant, expressed in baculovirus infected insect cells, ≥50% (SDS-PAGE)

동의어(들):

dual specificity tyrosine-phosphorylation-regulated kinase 2

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About This Item

UNSPSC 코드:
12352200
NACRES:
NA.32

생물학적 소스

human

재조합

expressed in baculovirus infected insect cells

분석

≥50% (SDS-PAGE)

형태

aqueous solution

분자량

63.5 kDa

포장

pkg of 10 μg

농도

>0.02 mg/mL

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−70°C

유전자 정보

human ... DYRK2(8445)

일반 설명

Human DYRK2 (GenBank Accession No. NM_003583), full length with N-terminal His tag, MW = 63.5 kDa, expressed in Baculovirus infected Sf9 cell expression system.

애플리케이션

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

물리적 형태

TBST+20% glycerol+3mM DTT

제조 메모

Thaw on ice. Upon first thaw, briefly spin tube containing enzyme to recover full content of the tube. Aliquot enzyme into single use aliquots. Store remaining undiluted enzyme in aliquots at -70°C. Note: Enzyme is very sensitive to freeze/thaw cycles.

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Rosario Morrugares et al.
Cellular and molecular life sciences : CMLS, 77(13), 2621-2639 (2019-10-13)
NOTCH proteins constitute a receptor family with a widely conserved role in cell cycle, growing and development regulation. NOTCH1, the best characterised member of this family, regulates the expression of key genes in cell growth and angiogenesis, playing an essential
Isao Kii et al.
Nature communications, 7, 11391-11391 (2016-04-23)
Autophosphorylation of amino-acid residues is part of the folding process of various protein kinases. Conventional chemical screening of mature kinases has missed inhibitors that selectively interfere with the folding process. Here we report a cell-based assay that evaluates inhibition of
Martin Mehnert et al.
Nature communications, 11(1), 3563-3563 (2020-07-18)
Rapidly increasing availability of genomic data and ensuing identification of disease associated mutations allows for an unbiased insight into genetic drivers of disease development. However, determination of molecular mechanisms by which individual genomic changes affect biochemical processes remains a major

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