SML3908
SLU-PP-332
≥98% (HPLC)
동의어(들):
(E)-4-Hydroxy-N′(naphthalen-2-ylmethylene)benzohydrazide, 4-Hydroxybenzoic acid 2-(2-naphthalenylmethylene)hydrazide, ERR pan-Agonist 332, SR9861
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C18H14N2O2
CAS Number:
Molecular Weight:
290.32
MDL number:
UNSPSC 코드:
51111800
UNSPSC 코드:
12352200
추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
저장 온도
2-8°C
SMILES string
OC1=CC=C(C=C1)C(N/N=C/C2=CC3=C(C=C2)C=CC=C3)=O
생화학적/생리학적 작용
Non-toxic pan ERRα/β/γ agonist with significant ERRα activity that acts as an exercise mimetic.
SLU-PP-332 is a non-toxic pan ERRα/β/γ (estrogen receptor-related receptors α/β/γ) agonist with significant ERRα activity (EC50 = 98, 230 & 430 nM against ERRα, ERRβ & ERγ) and acts as an exercise mimetic. SLU-PP-332 displays selectivity over ERα, ERβ and several other closely related nuclear receptors. It induces Ddit4 expression and enhances mitochondrial respiration in C2C12 myocytes (10 µM) and exercise endurance in mice (50 mg/kg bid, ip) in an ERRα-dependent manner.
SLU-PP-332 is a non-toxic pan ERRα/β/γ (estrogen receptor-related receptors α/β/γ) agonist with significant ERRα activity (EC50 = 98, 230 & 430 nM against ERRα, ERRβ & ERγ) and acts as an exercise mimetic. SLU-PP-332 displays selectivity over ERα, ERβ and several other closely related nuclear receptors. It induces Ddit4 expression and enhances mitochondrial respiration in C2C12 myocytes (10 µM) and exercise endurance in mice (50 mg/kg bid, ip) in an ERRα-dependent manner.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
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