SML3846

Motixafortide trifluoroacetate

≥95% (HPLC)

• 동의어(들): TF 14016 trifluoroacetate, B 4F-benzoyl-TN14003 trifluoroacetate, BKT 140 trifluoroacetate, BKT140 trifluoroacetate, N2-(4-Fluorobenzoyl)-L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-D-lysyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl- L-argininamide cyclic (4→13)-disulfide trifluoroacetate, TF14016 trifluoroacetate
• 실험식(Hill 표기법): C₉₇H₁₄₄FN₃₃O₁₉S₂ · xC₂HF₃O₂
• Molecular Weight: 2159.52 (free base basis)
• UNSPSC 코드: 12352200

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 형태: (Powder or Lyophilized powder or film)
• 저장 조건: desiccated
• 색상: white to off-white
• 저장 온도: -10 to -25°C
• SMILES string: O=C(NCCCC1NC(C(CCCNC(N)=N)NC(C(CC2=CC=C(C=C2)O)NC(C3N(CCC3)C(C(CCCCN)NC(C(CCCCN)NC(C(CCCNC(N)=O)NC(C(CC4=CC=C(C=C4)O)NC(C(CSSCC(C(NC(CCCNC(N)=N)C(N)=O)=O)NC1=O)NC(C(CC5=CC6=C(C=CC=C6)C=C5)NC(C(CCCNC(N)=N)NC(C(CCCNC(N)=N)NC(C7=CC=C(C=C7)F)=O)=O)=O)=O)=O)=O

설명

생화학적/생리학적 작용

Motixafortide (BKT140, BL-8040) is an orally available, highly selective inverse agonist of CXCR4 (CXC Chemokine Receptor 4). Motixafortide is a potent stem cell mobiliser and anticancer agent. BKT140 potently inhibits CXCL12 induced migration/invasion of small-cell lung cancer cells.

주의사항

Hygroscopic

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable