SML3823

KCI807

≥98% (HPLC)

• 동의어(들): 5,3’-Dihydroxyflavone, 5-Hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-one
• 실험식(Hill 표기법): C₁₅H₁₀O₄
• CAS Number: 6665-68-5
• Molecular Weight: 254.24
• MDL number: MFCD00143394
• UNSPSC 코드: 51111800
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: 0.2 mg/mL (DMSO:EtOH (2:1),clear, warmed, clear colorless solution)
• 저장 온도: room temp
• SMILES string: [o]1c2c([c](cc1c3cc(ccc3)O)=O)c(ccc2)O
• InChI key: SZMQXDYEGKRZDG-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction

KCI807 is a cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction. KCI807 interrupts association of the androgen receptor (AR) with transcription activator ELK1 (ETS family transcription factor ELK1). It potently suppresses growth of enzalutamide-resistant prostate cancer tumor xenografts in rodents.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable