SML3740

PY-60

≥98% (HPLC)

• 동의어(들): 5-Phenyl-N-[3-(2-thiazolyl)propyl]-3-isoxazolecarboxamide
• 실험식(Hill 표기법): C₁₆H₁₅N₃O₂S
• CAS Number: 2765218-56-0
• Molecular Weight: 313.37
• MDL number: MFCD34474253
• UNSPSC 코드: 12352200
• NACRES: NA.21

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: -10 to -25°C

설명

생화학적/생리학적 작용

PY-60 is a potent and specific activator of the transcriptional coactivator Yes-associated protein 1 (YAP) signaling. It stimulates YAP-dependent expansion of epidermal keratinocytes in mouse. PY-60 binds directly to annexin A2 (ANXA2) causing its liberation and YAP activation.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable