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Merck
모든 사진(1)

주요 문서

SML2947

Sigma-Aldrich

Penehyclidine hydrochloride

≥98% (HPLC)

동의어(들):

α-[(1-Azabicyclo[2.2.2]oct-3-yloxy)methyl]-α-cyclopentyl-benzenemethanol hydrochloride, 3-(2′-phenyl-2′-cyclopentyl-2′-hydroxyl-ethoxy) quinuclidine, Penequine hydrochloride, Penequinine

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About This Item

실험식(Hill 표기법):
C20H29NO2 · HCl
CAS Number:
Molecular Weight:
351.91
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

양식

powder (hygroscopic)

저장 조건

desiccated

색상

white to beige

solubility

H2O: 2 mg/mL, clear

저장 온도

−20°C

SMILES string

[Cl-].N21CC(C(CC2)CC1)OCC(O)(C4CCCC4)c3ccccc3.[H+]

InChI

1S/C20H29NO2.ClH/c22-20(18-8-4-5-9-18,17-6-2-1-3-7-17)15-23-19-14-21-12-10-16(19)11-13-21;/h1-3,6-7,16,18-19,22H,4-5,8-15H2;1H

InChI key

DDTVVMRZNVIVQM-UHFFFAOYSA-N

생화학적/생리학적 작용

Penehyclidine hydrochloride is a brain penetrant anticholinergic drug that exhibits both antimuscarinic and antinicotinic activity. Penehyclidine hydrochloride does not induce muscarinic 2 receptor-associated cardiovascular side effects. Penehyclidine hydrochloride is effective in experimental models of heart, lung and brain ischemia reperfusion injury.
brain penetrant anticholinergic drug that exhibits both antimuscarinic and antinicotinic activity

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Yong-An Wang et al.
Life sciences, 78(2), 210-223 (2005-09-13)
Previous studies have paid little attention to the anticonvulsant effect of anticholinergic drugs that act on both muscarinic (M) and nicotinic (N) receptors during soman-induced seizures. Therefore, with the establishment of a soman-induced seizures model in rats, this study evaluated

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