SML2630

Intronistat B hydrobromide

≥98% (HPLC)

• 동의어(들): N-(2-(Pyrrolidin-1-yl)ethyl)-2-(3,4,5-trihydroxybenzoyl) benzofuran-5-carboxamide hydrobromide
• 실험식(Hill 표기법): C₂₂H₂₂N₂O₆ · xHBr
• Molecular Weight: 410.42 (free base basis)
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to dark gray
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C

설명

생화학적/생리학적 작용

Inhibitor of the self-splicing group IIB intron found in fungi

Intronistat B is a potent inhibitor of the self-splicing group IIB intron, a mitochondrial RNA tertiary structure necessary for respiration in fungi, yeast and plants, but not found in vertebrates. Intronistat B was found to have antifungal activity comparable to that of amphotericin B in inhibiting growth of the Candida parapsilosis. It did not inhibit spliceosomal processing, group I intron splicing or splicing of group II introns from subclasses other than subclass IIB and was not toxic to human cells.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3