SML2611

Bobcat339

≥98% (HPLC)

• 동의어(들): 1-([1,1′-Biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one, 4-Amino-1-[1,1′-biphenyl]-3-yl-5-chloro-2(1H)-pyrimidinone
• 실험식(Hill 표기법): C₁₆H₁₂ClN₃O
• CAS Number: 2280037-51-4
• Molecular Weight: 297.74
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: NC1=NC(N(C2=CC=CC(C3=CC=CC=C3)=C2)C=C1Cl)=O
• InChI: 1S/C16H12ClN3O/c17-14-10-20(16(21)19-15(14)18)13-8-4-7-12(9-13)11-5-2-1-3-6-11/h1-10H,(H2,18,19,21)
• InChI key: QMGYGOOYCNTEQO-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Bobcat339 is a cell penetrant, potent and selective inhibitor of TET1 and TET2 [Ten-eleven translocation methylcytosine dioxygenase (TET) 1 and 2] that reduces content of 5-hydroxymethyl-cytosine (5hmC) in cultured neurons. Bobcat339 does not inhibit DNMT3a.

cell penetrant, potent and selective inhibitor of TET1 and TET2

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable