SML2187

RL5a

≥98% (HPLC)

• 동의어(들): N2-[2-(2-Furanyl)-4-quinolinyl]-N1,N1-dimethyl-1,2-ethanediamine
• 실험식(Hill 표기법): C₁₇H₁₉N₃O
• CAS Number: 133671-66-6
• Molecular Weight: 281.35
• MDL number: MFCD00929354
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to very dark brown
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: N(CCNc1c2c(nc(c1)c3[o]ccc3)cccc2)(C)C
• InChI: 1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19)
• InChI key: CRGKLHXVNVZAPA-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to origin DNA, which is required interaction for licensing. RL5a appears to act as noncompetitive inhibitor of ORC with respect to ATP.

potent inhibitor of the replication licensing system.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3