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Merck
모든 사진(1)

Key Documents

추가 자료

SML2070

Sigma-Aldrich

23-Hydroxybetulinic acid

≥98% (HPLC)

동의어(들):

(3β,4α)-3,23-Dihydroxylup-20(29)-en-28-oic acid, 3β,23-Dihydroxylup-20(29)-en-28-oic acid, 3aH-Cyclopenta[a]chrysene, lup-20(29)-en-28-oic acid deriv., Anemosapogenin

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C30H48O4
CAS Number:
85999-40-2
Molecular Weight:
472.70
MDL number:
MFCD28126999
UNSPSC 코드:
12352106
NACRES:
NA.77

분석

≥98% (HPLC)

형태

powder

저장 조건

under inert gas

색상

white to beige

solubility

DMSO: 2 mg/mL, clear

저장 온도

−20°C

SMILES string

O[C@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC[C@@]4([H])[C@@]3(C)CC[C@]5(C(O)=O)[C@]4([H])[C@H](C(C)=C)CC5)([H])[C@]1(C)CO

InChI

1S/C30H48O4/c1-18(2)19-9-14-30(25(33)34)16-15-28(5)20(24(19)30)7-8-22-26(3)12-11-23(32)27(4,17-31)21(26)10-13-29(22,28)6/h19-24,31-32H,1,7-17H2,2-6H3,(H,33,34)/t19-,20+,21+,22+,23-,24+,26-,27-,28+,29+,30-/m0/s1

InChI key

HXWLKAXCQLXHML-WGOZWDAUSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

23-Hydroxybetulinic acid is a cytotoxic agent from rizoma of Pulsatilla chinensis (Bunge) Regel. Anticancer activity of 23-Hydroxybetulinic acid is associated with depolarizations of the mitochondrial membrane potential and subsequent cell apoptosis. Additionally it induces autophagic cell death in HL-60 cells via the up regulation of Beclin-1.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Nan Yao et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 37(3), 838-852 (2015-09-19)
Hepatocellular carcinoma (HCC) is the most common type of liver cancer. At present, only sorafenib is approved to treat HCC. In this study, we found that a 23-hydroxybetulinic acid derivative, B4G2, exhibited potent antiproliferative activity in HCC cell lines. We
Yi Bi et al.
Molecules (Basel, Switzerland), 17(8), 8832-8841 (2012-07-27)
23-Hydroxybetulinic acid (1) served as the precursor for the synthesis of C-28 ester derivatives. The target compounds were evaluated in vitro for their antitumor activities against five cell lines (A549, BEL-7402, SF-763, B16 and HL-60). Among the obtained compounds, 6i
Ming Liu et al.
Pharmaceutical biology, 53(1), 1-9 (2014-07-16)
The rizoma of Pulsatilla chinensis (Bunge) Regel has been used as a traditional Chinese medicinal herb for thousands of years. Total saponins from P. chinensis can induce the apoptosis of solid cancer cells; however, their activity on chronic myeloid leukemia

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