SML1523
Estetrol
≥98% (HPLC)
동의어(들):
15α-Hydroxyestriol, 3,15α,16α,17β-Tetrahydroxyestra-1,3,5(10)-triene, E4, Estra-1,3,5(10)-triene-3,15α,16α,17β-tetrol, Oestetrol
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C18H24O4
CAS Number:
Molecular Weight:
304.38
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder
solubility
DMSO: 20 mg/mL, clear
저장 온도
−20°C
SMILES string
[H][C@@]12CCC3=CC(O)=CC=C3[C@@]1([H])CC[C@@]4(C)[C@@]2([H])[C@@H](O)[C@@H](O)[C@@H]4O
InChI
1S/C18H24O4/c1-18-7-6-12-11-5-3-10(19)8-9(11)2-4-13(12)14(18)15(20)16(21)17(18)22/h3,5,8,12-17,19-22H,2,4,6-7H2,1H3/t12-,13-,14-,15-,16-,17+,18+/m1/s1
InChI key
AJIPIJNNOJSSQC-NYLIRDPKSA-N
일반 설명
Estetrol is an estrogenic steroid molecule produced exclusively during pregnancy by the fetal liver.
생화학적/생리학적 작용
Estetrol (E4, 15α-Hydroxyestriol) is an estrogen steroid hormone produced exclusively during pregnancy by the fetal liver. Estetrol is a selective estrogen receptor modulator (SERM) with potent estrogenic effects on vaginal mucosa, bone and brain, neutral effect on liver, and anti-estrogen effects on breast tissue. Estetrol has higher affinity for ERα over ERβ. Estetrol is being studied for its potential as a contraceptive, a drug for meopausal symptoms, and an anticancer agent.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Christian F Holinka et al.
The Journal of steroid biochemistry and molecular biology, 110(1-2), 138-143 (2008-05-09)
Estetrol (E(4)) is an estrogenic steroid molecule synthesized exclusively by the fetal liver during human pregnancy and reaching the maternal circulation through the placenta. Its function is presently unknown. After its discovery in the mid-1960s, E(4) research revealed rather unique
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