SML1483

Ogerin negative control

≥98% (HPLC)

• 동의어(들): 3-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-benzenemethanol
• 실험식(Hill 표기법): C₁₇H₁₇N₅O
• CAS Number: 1125453-08-8
• Molecular Weight: 307.35
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825912
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: NC1=NC(C2=CC(CO)=CC=C2)=NC(NCC3=CC=CC=C3)=N1
• InChI: 1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22)
• InChI key: RVKAHYFWSKSSQQ-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Ogerin negative control is a structurally similar analog of ogerin (catalog no. SML1482). Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. The meta-analog is inactive and serves as a negative control.

추천 제품

The positive allosteric modulator, ogerin, is available from Sigma. To learn more about and purchase ogerin, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable