SML1370

A-779 trifluoroacetate salt

≥98% (HPLC)

• 동의어(들): A779 trifluoroacetate salt, Asp1-Arg2-Val3-Tyr4-Ile5-His6-D-Ala7, D-Ala7-Ang-(1-7), DRVYIHA (Modification: Ala-7 = D-Ala), DRVYIHa trifluoroacetate salt, H-Asp-Arg-Val-Tyr-Ile-His-D-Ala-OH trifluoroacetate salt, [7-D-ALA]-angiotensin-(1-7) trifluoroacetate salt
• 실험식(Hill 표기법): C₃₉H₆₀N₁₂O₁₁ · xC₂HF₃O₂
• CAS Number: 159432-28-7
• Molecular Weight: 872.97 (free base basis)
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: lyophilized powder
• 색상: white to off-white
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

생화학적/생리학적 작용

A-779 (D-Ala7-Ang-(1-7)) is a potent and selective antagonist of angiotensin (1-7), an endogenous peptide that acts through activation of a non-AT1, non-AT2 receptor, Mas, and opposes the activity of angiotensin. A-779 has an IC₅₀ of 0.3 nM for Mas with negligible affinity for either AT1R or AT2R.

A-779 is a potent and selective antagonist of angiotensin (1-7).

This blocking angiotensin action affects cardiovascular function.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable