SML1172

FFN102

≥98% (HPLC)

• 동의어(들): 4-(2-Amino-ethyl)-6-chloro-7-hydroxy-chromen-2-one trifluoroacetate, 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one trifluoroacetate, Mini 102, Mini102
• 실험식(Hill 표기법): C₁₁H₁₀ClNO₃ · CF₃CO₂H
• CAS Number: 1234064-11-9
• Molecular Weight: 353.68
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825700
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to light brown
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: FC(F)(F)C(O)=O.NCCC(C1=CC(Cl)=C(O)C=C1O2)=CC2=O
• InChI: 1S/C11H10ClNO3.C2HF3O2/c12-8-4-7-6(1-2-13)3-11(15)16-10(7)5-9(8)14;3-2(4,5)1(6)7/h3-5,14H,1-2,13H2;(H,6,7)
• InChI key: OGHPXKAKVMJGQH-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

FFN102 is a pH-responsive fluorescent false neurotransmitter that acts as a dopamine transporter substrate (DAT) and also a substrate for vesicular monoamine transporter 2 (VMAT2).

FFN102 is a pH-responsive fluorescent false neurotransmitter that acts as a dopamine transporter substrate (DAT) and also a substrate for vesicular monoamine transporter 2 (VMAT2). FFN102 selectively labels dopamine cell bodies and dendrites in ventral midbrain and dopaminergic synaptic terminals in dorsal striatum. Its greater fluorescence emission in neutral than acidic environments allows the visualization of dopamine release at individual presynaptic terminals and in situ pH measurement of catecholamine secretory vesicles.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable