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Merck
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Key Documents

SML1042

Sigma-Aldrich

Eptifibatide acetate

≥98% (HPLC)

동의어(들):

Cyclo(S,S)-Mpr(Har)GDWPC-NH2 acetate, N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide cyclic (16)-disulfide acetate

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About This Item

실험식(Hill 표기법):
C35H49N11O9S2 · xC2H4O2
CAS Number:
Molecular Weight:
831.96 (free base basis)
UNSPSC 코드:
51111800
NACRES:
NA.77

분석

≥98% (HPLC)

형태

powder

저장 조건

desiccated

색상

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

배송 상태

wet ice

저장 온도

−20°C

일반 설명

Eptifibatide acetate is a cyclic heptapeptide. It is the member of the class arginin-glycin-aspartat-mimetics. Eptifibatide has a short half-life. The drug decreases the risk of myocardial infarction (MI). Eptifibatide acetate might be associated with thrombocytopenia.

생화학적/생리학적 작용

Eptifibatide is a specific inhibitor of fibrinogen binding to the platelet membrane integrin glycoprotein GPIIb/IIIa receptor, preventing platelet aggregation. Eptifibatide binds reversibly and competitively.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes
Bhatt DL and Topol EJ
JAMA : The Journal of the American Medical Association, 284(12), 1549-1558 (2000)
Eptifibatide: A cyclic peptide that selectively inhibits platelet glycoprotein IIb/IIIa
Heras M and Escolar G
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