SML0445

Clemastine fumarate salt

≥98% (HPLC)

• 동의어(들): (+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate salt, (2R)-2-[2-[(1R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine fumarate salt, 1-Methyl-2-[2-(α-methyl-p-chlorobenzhydryloxy)ethyl]pyrrolidine fumarate salt, 1-Methyl-2-[2-(methyl-p-chlorodiphenylmethyloxy)ethyl]pyrrolidine fumarate salt, Meclastine fumarate salt, Mecloprodine
• 실험식(Hill 표기법): C₂₁H₂₆ClNO · C₄H₄O₄
• CAS Number: 14976-57-9
• Molecular Weight: 459.96
• EC Number: 239-055-2
• MDL number: MFCD00137486
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329824727
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D +15 to +25°, c = 1 in methanol
• 저장 조건: desiccated
• 색상: white to beige
• solubility: DMSO: 5 mg/mL (clear solution; warmed)
• 저장 온도: room temp
• SMILES string: OC(=O)\C=C\C(O)=O.CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3
• InChI: 1S/C21H26ClNO.C4H4O4/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2;5-3(6)1-2-4(7)8/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t20-,21-;/m1./s1
• InChI key: PMGQWSIVQFOFOQ-YKVZVUFRSA-N
• 유전자 정보: human ... HRH1(3269)

설명

일반 설명

Clemastine fumarate is used to treat multiple sclerosis, sneezing and rhinorrhea linked to common cold. It stimulates oligodendrocyte progenitor cell (OPC) differentiation and myelination.

애플리케이션

Clemastine fumarate salt has been used as a stimulator of rodent oligodendrocyte generation and myelination in vitro and in vivo.

생화학적/생리학적 작용

Clemastine fumarate is an antihistamine H1-antagonist and anticholinergic that also has antipruritic activity.

특징 및 장점

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable