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Merck
모든 사진(1)

주요 문서

SML0379

Sigma-Aldrich

Nodinitib-1

≥98% (HPLC)

동의어(들):

1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-amine, CID-1088438, ML130

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크기 선택

100 G
PLN 553.00

PLN 553.00


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크기 선택

보기 변경
100 G
PLN 553.00

About This Item

실험식(Hill 표기법):
C14H13N3O2S
CAS Number:
Molecular Weight:
287.34
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
NACRES:
NA.77

PLN 553.00


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Quality Level

분석

≥98% (HPLC)

양식

powder

색상

white to beige

solubility

DMSO: >10 mg/mL

저장 온도

2-8°C

SMILES string

NC1=NC2=C(N1S(C3=CC=C(C)C=C3)(=O)=O)C=CC=C2

InChI

1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)

InChI key

SRFABRWQVPCPRG-UHFFFAOYSA-N

생화학적/생리학적 작용

Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2.
Nodinitib-1 is a selective inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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