SML0295
Dihydromyricetin
≥98% (HPLC)
동의어(들):
(2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one, 3,3′,4′,5,5′,7-Hexahydroxyflavanone, Ampelopsin, Ampeloptin, DHM
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C15H12O8
CAS Number:
Molecular Weight:
320.25
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
양식
powder
저장 조건
protect from light
색상
white to beige
solubility
DMSO: ≥5 mg/mL (warmed)
저장 온도
−20°C
SMILES string
O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(C(O)=C3)O)[C@H]1O
InChI
1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
InChI key
KJXSIXMJHKAJOD-LSDHHAIUSA-N
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일반 설명
Dihydromyricetin is a major flavonoid present in A. grossedentata.
애플리케이션
Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.
생화학적/생리학적 작용
Dihydromyricetin (Ampelopsin) is a flavanonol with antioxidant and anti-cancer activity, found to have anti-alcohol intoxication effects. Its anti-alcohol effects appear to be by its actions as a positive modulator of GABA-A receptors at the benzodiazepine site.
Dihydromyricetin possesses anti-inflammatory action.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
Yanjun Shi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 87, 251-257 (2011-12-20)
The interaction between bovine serum albumin (BSA) and the anticancer drug molecule ampelopsin (AMP) was investigated using fluorescence spectroscopy, circular dichroism (CD) spectra, and time-resolved spectra under simulated physiological conditions. Fluorescence data showed that the intrinsic fluorescence of BSA was
Wei-Ming Zhou et al.
Molecules (Basel, Switzerland), 15(4), 2114-2123 (2010-04-30)
This study reports two novel 5-fluorouracil-substituted ampelopsin derivatives. The structures of two new derivatives were characterized by elemental analysis, 1H-NMR, 13C-NMR, IR and MS. Their anticancer activities in vitro against two cancer cell lines, K562 and K562/ADR, were investigated using
Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down-regulation of phosphorylation of PPARgamma in 3T3-L1 cells
Liu L, et al.
Journal of Cellular and Molecular Medicine, 22(2), 1247-1256 (2018)
Shimei Qi et al.
International immunopharmacology, 12(1), 278-287 (2011-12-24)
Ampelopsin (AMP), a plant flavonoid, has potent anti-inflammatory properties in vitro and in vivo. The molecular mechanisms of ampelopsin on pharmacological and biochemical actions of RAW264.7 macrophages in inflammation have not been clearly elucidated yet. In the present study, non-cytotoxic
Feng Ni et al.
PloS one, 7(6), e38802-e38802 (2012-06-14)
The objective of this study was to evaluate the chemopreventive effect of a novel flavonoid, ampelopsin (AMP) on the growth and metastasis of prostate cancer cells. AMP showed the more potent activity in inhibiting the proliferation of androgen-sensitive LNCaP and
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