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Merck
모든 사진(1)

Key Documents

SMB01077

Sigma-Aldrich

Poliothyrsoside

≥85% (LC/MS-ELSD)

동의어(들):

Nigracin

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C20H22O9
CAS Number:
Molecular Weight:
406.38
MDL number:
UNSPSC 코드:
12352205
NACRES:
NA.25

생물학적 소스

plant

분석

≥85% (LC/MS-ELSD)

형태

solid

분자량

406.38

응용 분야

metabolomics
vitamins, nutraceuticals, and natural products

저장 온도

−20°C

InChI

1S/C20H22O9/c21-9-12-8-13(22)6-7-14(12)28-20-18(25)17(24)16(23)15(29-20)10-27-19(26)11-4-2-1-3-5-11/h1-8,15-18,20-25H,9-10H2/t15-,16-,17+,18-,20-/m1/s1

InChI key

FLROYCKIIJCTDY-BFMVXSJESA-N

일반 설명

Poliothyrsoside, also known as Nigracin, is a phenolic glycoside compound commonly found in plants such as Flacourtia indica, Loxocalyx urticifolius, Hydnocarpus annamensis, Xylosma flexuosa, Poliothyrsis sinensis, and Scolopia spinosa. Existing research suggests that this plant-derived metabolite exerts various biological activities, antioxidant, antidiabetic, anti-alzheimers and antiplasmodial properties.

애플리케이션

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

생화학적/생리학적 작용

Poliothyrsoside is a pyruvic transaminase inhibitor known for its insulin-sensitizing effects in cell culture. Additionally, it exhibits anti-diabetic properties by inhibiting acetyl-CoA carboxylase, ultimately enhancing insulin sensitivity and lowering blood glucose levels in diabetic mice. This compound also serves as a lactate dehydrogenase inhibitor and demonstrates antidepressant-like actions, along with effectiveness against Alzheimer′s disease. In vitro studies have further revealed Poliothyrsoside′s capacity to inhibit virus production and exhibit antiviral activity against HIV-1.

특징 및 장점

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

기타 정보

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Gianluca Sferrazza et al.
Frontiers in pharmacology, 10, 1541-1541 (2020-02-11)
Drypetes klainei Pierre ex Pax is used in Cameroon by Baka people in the wound healing process and for the treatment of burns. In a previous paper we demonstrated the ability of both water (WE) and defatted methanol (DME) extracts

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