콘텐츠로 건너뛰기
Merck
모든 사진(1)

Key Documents

SMB01002

Sigma-Aldrich

Guineensine

≥90% (LC/MS-ELSD)

동의어(들):

(2E,4E,12E)-13-(1,3-benzodioxol-5-yl)-N-isobutyl-trideca-2,4,12-trienamide, Pipyahyine

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C24H33NO3
CAS Number:
Molecular Weight:
383.52
MDL number:
UNSPSC 코드:
12352205
NACRES:
NA.25

생물학적 소스

plant

분석

≥90% (LC/MS-ELSD)

형태

solid

분자량

383.52

solubility

water: slightly soluble

응용 분야

metabolomics
vitamins, nutraceuticals, and natural products

저장 온도

−20°C

InChI

1S/C24H33NO3/c1-20(2)18-25-24(26)14-12-10-8-6-4-3-5-7-9-11-13-21-15-16-22-23(17-21)28-19-27-22/h8,10-17,20H,3-7,9,18-19H2,1-2H3,(H,25,26)/b10-8+,13-11+,14-12+

InChI key

FPMPOFBEYSSYDQ-AUVZEZIHSA-N

일반 설명

Guineensine, also known as Pipyahyine, is an alkaloid and a member of benzodioxoles is a natural product commonly available from Piper Sp.(P. nigrum and P. longum and P. retrofractum) plants. Existing research suggests that this plant-derived metabolite exerts various biological activities, including antimicrobial, anticancer, anti-inflammatory, antiviral and antioxidant properties.

애플리케이션

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

생화학적/생리학적 작용

According to the existing research, Guineensine inhibits endocannabinoid uptake, leading to significant anti-inflammatory and analgesic effects, and also interacts with various receptors, including dopamine transporter DAT, 5HT2A, and sigma receptors, suggesting potential polypharmacological activity.

특징 및 장점

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

기타 정보

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Ruben Bartholomäus et al.
ChemMedChem, 14(17), 1590-1596 (2019-07-20)
Guineensine ((2E,4E,12E)-13-(benzo[d][1,3]dioxol-5-yl)-N-isobutyltrideca-2,4,12-trienamide) is a plant-derived natural product that inhibits reuptake of the endocannabinoid anandamide with sub-micromolar potency. We have established a highly efficient total synthesis of guineensine, which provided the natural product in only five steps from commercially available 3-nonyn-1-ol

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.