분석
≥95% (HPLC)
배송 상태
wet ice
저장 온도
−20°C
InChI
1S/C26H43NO7S/c1-16(4-9-23(28)27-15-24(29)30)20-7-8-21-19-6-5-17-14-18(34-35(31,32)33)10-12-25(17,2)22(19)11-13-26(20,21)3/h16-22H,4-15H2,1-3H3,(H,27,28)(H,29,30)(H,31,32,33)/p-1/t16-,17-,18-,19+,20-,21+,22+,25+,26-/m1/s1
InChI key
FHXBAFXQVZOILS-OETIFKLTSA-M
일반 설명
Sulfoglycolithocholic acid, also known as sulfolithocholylglycine, belongs to the class of compounds referred as glycinated bile acids and derivatives. This compound serves as a valuable asset in both biochemical and metabolomics research due to its significant role in the field of bile acid conjugates and secondary bile acid production. Sulfolithocholylglycine is the 3-O-sulfo derivative of glycolithocholic acid and is synthesized through microbial flora enzymes in the colonic environment. In hepatocytes, bile acids, both primary and secondary, undergo amino acid conjugation at the C-24 carboxylic acid on the side chain, resulting in the predominance of glycine-conjugated forms of bile acids in the bile duct. This compound′s unique properties make it an intriguing subject for research, with potential applications in metabolomics and biochemistry.
애플리케이션
Sulfoglycolithocholic acid can be used in biochemical research and metabolomics research. It can be used to study the metabolism of bile acids, the gut microbiome, and the effects of bile acids on various tissues and organs.
특징 및 장점
- Can be used in Metabolomics and Biochemical research
- High-quality compound suitable for multiple research applications
기타 정보
For additional information on our range of Biochemicals, please complete this form.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Takaaki Goto et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 846(1-2), 69-77 (2006-09-05)
We developed a highly sensitive and quantitative method to detect bile acid 3-sulfates in human urine employing liquid chromatography/electrospray ionization-tandem mass spectrometry. This method allows simultaneous analysis of bile acid 3-sulfates, including nonamidated, glycine-, and taurine-conjugated bile acids, cholic acid
Thierry Claudel et al.
Arteriosclerosis, thrombosis, and vascular biology, 25(10), 2020-2030 (2005-07-23)
Bile acids are the end products of cholesterol metabolism. They are synthesized in the liver and secreted via bile into the intestine, where they aid in the absorption of fat-soluble vitamins and dietary fat. Subsequently, bile acids return to the
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