SMB00370
Tetrahydrocurcumin
≥96% (HPLC)
동의어(들):
Tetrahydrocurcumin, 1,7-bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione, HZIV 81-2, NSC687845, Tetrahydrodiferuloylmethane, 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C21H24O6
CAS Number:
Molecular Weight:
372.41
Beilstein:
3485469
MDL number:
UNSPSC 코드:
12352205
PubChem Substance ID:
NACRES:
NA.25
추천 제품
Quality Level
분석
≥96% (HPLC)
양식
powder
응용 분야
metabolomics
vitamins, nutraceuticals, and natural products
저장 온도
−20°C
SMILES string
COc1cc(CCC(=O)CC(=O)CCc2ccc(O)c(OC)c2)ccc1O
InChI
1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3
InChI key
LBTVHXHERHESKG-UHFFFAOYSA-N
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일반 설명
Tetrahydrocurcumin (THC) is a colorless metabolite of curcumin. It has a similar structure to that of curcumin. THC lacks the α, β-unsaturated carbonyl moiety in its chemical structure. It is naturally sourced from the roots of Curcuma zedoaria, Zingiber mioga, and Zingiber officinale.
애플리케이션
Tetrahydrocurcumin (THC) has been used as a neuroprotective agent to study its therapeutic potential in improving mitochondrial dysfunction in the ischemic stroke mice model.
생화학적/생리학적 작용
Tetrahydrocurcumin is well-studied in treating cancer for its excellent anti-cancer, anti-angiogenic, and chemopreventative activities. It also exerts anti-inflammatory properties. Tetrahydrocurcumin has been shown to have antioxidant and protective effects against diabetes, and vascular dysfunction via alleviation of oxidative stress.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
385.2 °F
Flash Point (°C)
196.2 °C
이미 열람한 고객
Pooja Maharjan et al.
Archives of pharmacal research, 42(10), 909-925 (2019-04-29)
Ocular drug delivery has been a well-known route for the drug administration for the treatment of ocular diseases. However, numerous anatomical and physiological barriers prevailing in the eye itself create considerable challenges for achieving the necessitated therapeutic efficacy along with
Bharat B Aggarwal et al.
Molecules (Basel, Switzerland), 20(1), 185-205 (2014-12-31)
Curcumin (diferuloylmethane), a golden pigment from turmeric, has been linked with antioxidant, anti-inflammatory, anticancer, antiviral, antibacterial, and antidiabetic properties. Most of the these activities have been assigned to methoxy, hydroxyl, α,β-unsaturated carbonyl moiety or to diketone groups present in curcumin.
Nandan K Mondal et al.
Neurochemistry international, 122, 120-138 (2018-11-26)
The objectives of this study are to identify the mechanism of mitochondrial dysfunction during cerebral ischemic/reperfusion (I/R) injury and the therapeutic potential of tetrahydrocurcumin (THC) to mitigate mitochondrial dysfunction in experimental stroke model. In our study, 8-10 weeks old male
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