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Merck
모든 사진(1)

주요 문서

SCP0136

Sigma-Aldrich

Endothelin β Receptor Antagonist IRL 1038

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About This Item

실험식(Hill 표기법):
C68H92N14O15S2
Molecular Weight:
1409.67
UNSPSC 코드:
12352200
NACRES:
NA.32

분석

≥95% (HPLC)

양식

lyophilized

구성

Peptide Content, ≥67%

저장 조건

protect from light

저장 온도

−20°C

Amino Acid Sequence

Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp

애플리케이션

IRL-1038 is used as a specific endothelin-B receptor (ET(B)-R) antagonist/blocker.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Hung-Tien Kuo et al.
The Kaohsiung journal of medical sciences, 22(8), 371-376 (2006-08-17)
Angiotensin II (Ang-II) is a potent vasoactive hormone, which plays an important role in the pathogenesis of glomerulosclerosis. Ang-II activates many cytokine systems in the kidney. Recent studies indicate that Ang-II is closely related to the activation of the endothelin-1
Noreen F Rossi
American journal of physiology. Endocrinology and metabolism, 286(4), E535-E541 (2003-12-11)
The endothelins (ET) have been implicated in vasopressin (AVP) release in vivo and in vitro. The effects of ET in this system are complex, and the net AVP secretory response likely depends on a unique combination of ET isoform, ET
Guo-lin Zhang et al.
Acta pharmacologica Sinica, 32(2), 223-229 (2011-02-05)
To investigate which endothelin receptors mediated isoproterenol (ISO)-induced downregulation of FKBP12.6/12 in cardiomyocytes and study whether argirhein, a novel compound containing rhein and L-arginine that has anti-inflammatory activity, could reverse the downregulation of FKBP12.6/12 induced by ISO. Neonatal rat cardiomyocytes
Changaram S Venugopal et al.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 70(1), 50-57 (2006-03-22)
The purpose of this study was to evaluate the role of endothelin-1 (ET-1) and its receptors in the airway hyperreactivity of horses with obstructive pulmonary disease associated with summer pasture (SPAOPD). The right diaphragmatic lobe of the lung of 8

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